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The investigation of quindoxin photosensitivity
Author(s) -
Zaynoun S.,
Johnson B. E.,
FrainBell W.
Publication year - 1976
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1976.tb03073.x
Subject(s) - photosensitivity , dermatology , photosensitizer , contact dermatitis , medicine , photodermatosis , allergic contact dermatitis , sensitive skin , allergy , photochemistry , chemistry , immunology , materials science , xeroderma pigmentosum , optoelectronics , dna , biochemistry , dna damage
Quindoxin (quinoxaline di‐N‐oxide) is a photosensitizer capable of producing dermatitis. The study of a group of seven affected subjects has provided evidence of persistent light reaction and “photoallergy”, most probably to the parent substance and not to any photoproduct or contaminant. Clinical and photobiological similarities to the photo‐sensitivity dermatitis and actinic reticuloid syndrome were demonstrated.