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Allergic contact dermatitis from phenoxybenzamine hydrochloride Cross‐sensitivity to some related haloatkylamine compounds
Author(s) -
Mitchell J. C.,
Maibach H. I.
Publication year - 1975
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1975.tb05474.x
Subject(s) - sensitization , contact dermatitis , chemistry , hydrochloride , phenoxybenzamine , allergic contact dermatitis , dermatology , moiety , cross reactions , allergy , pharmacology , organic chemistry , medicine , immunology , biochemistry , receptor , antibody
Contact dermatitis from phenoxybenzamine hydrochloride occurred in a woman laboratory technician. Sensitization to this chemical was produced in guinea‐pigs. Cross‐sensitivity to related compounds may be due to the chloroethylamine moiety of the molecule. No cross‐sensitivity was observed to the dichlorodiethylamine compound, nitrogen mustard.