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Cinnamic aldehyde in toothpaste. 1. Clinical aspects and patch tests
Author(s) -
Magnusson B.,
Wilkinson D. S.
Publication year - 1975
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1975.tb05330.x
Subject(s) - patch test , toothpaste , medicine , dermatology , contact dermatitis , cosmetics , patch testing , allergic contact dermatitis , allergy , traditional medicine , dentistry , pathology , immunology
Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly‐formulated ‘spicy’ toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire and in Malmo and in a further eight patients discovered Subsequently. Similar symptoms and patch test results were observed independently at both centres. Positive reactions were obtained with 1 % cinnamic aldehyde in 15 out of 16 patients tested. Only one patient reacted to a standard sample of balsam of Peru (25 % in petrolatum).