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Difficulties in obtaining a sample of young adult cleft lip and palate subjects and their relatives
Author(s) -
Crawford Fiona C.,
Sofaer Jeffrey A.
Publication year - 1986
Publication title -
community dentistry and oral epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 101
eISSN - 1600-0528
pISSN - 0301-5661
DOI - 10.1111/j.1600-0528.1986.tb01533.x
Subject(s) - medicine , tonsillectomy , dentistry , pediatrics , surgery
Families of individuals aged 15–24 yr born with cleft lip, with or without cleft palate, and suitable control families were required for a study of inherited predisposition to the malformation. Cleft patients were identified through hospital discharge listings, but the overall yield of participating patients was only 8% of the cases listed. An attempt to recruit control subjects by the same method, using patients who had been hospitalized for dissection tonsillectomy, yielded only 4% of those identified as suitable in the discharge listings. The results highlight the value of specialized, regularly updated disease registers in the recruitment of subjects for research purposes.