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A manually controlled new device for punctuate mechanical stimulation of teeth during functional magnetic resonance imaging studies
Author(s) -
HabreHallage Pascale,
Hermoye Laurent,
Gradkowski Wojciech,
Jacobs Reinhilde,
Reychler Hervé,
Grandin Cécile B.
Publication year - 2010
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2010.01596.x
Subject(s) - functional magnetic resonance imaging , magnetic resonance imaging , somatosensory system , thumb , medicine , stimulation , neuroscience , dentistry , psychology , anatomy , radiology
Habre‐Hallage P, Hermoye L, Gradkowski W, Jacobs R, Reychler H, Grandin CB. A manually controlled new device for punctuate mechanical stimulation of teeth during functional magnetic resonance imaging studies. J Clin Periodontol 2010; 37: 863–872. doi: 10.1111/j.1600‐051X.2010.01596.x.Abstract Aim: To design a simple and affordable device that could apply standardized mechanical punctuate stimuli to trigger the periodontal mechanoreceptors during functional magnetic resonance imaging (fMRI). Material and Methods: A new manually controlled device using von Frey monofilaments was tested on a phantom and on eight volunteers. Four block design paradigms with different timing were compared. Teeth 11, 12, 13, 21, 22, 23 and the thumb were stimulated. Results: The device did not induce any artefacts in MR images. The most efficient protocol included an epoch duration of 24 s and stimuli delivered at 1 Hz. When stimulating the teeth, activations of the primary (S1) and secondary (S2) somatosensory areas were consistently obtained, either on the ipsilateral, contra‐lateral or both sides. Stimulation of the thumb led to activations of the contra‐lateral S1 area and either ipsilateral or contra‐lateral S2 area. Conclusion: The use of this innovative tool should allow to perform fMRI studies aimed to unveil the neural correlates of periodontal neural receptors, and to understand their plasticity induced by tooth loss and their eventual replacement by endosseous oral implants.