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Soft tissue volume augmentation by the use of collagen‐based matrices: a volumetric analysis
Author(s) -
Thoma Daniel S.,
Jung Ronald E.,
Schneider David,
Cochran David L.,
Ender Andreas,
Jones Archie A.,
Görlach Christoph,
Uebersax Lorenz,
GrafHausner Ursula,
Hämmerle Christoph H. F.
Publication year - 2010
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2010.01581.x
Subject(s) - soft tissue , volume (thermodynamics) , hard tissue , biomedical engineering , materials science , nuclear medicine , connective tissue , matrix (chemical analysis) , dentistry , medicine , surgery , pathology , composite material , physics , quantum mechanics
Thoma DS, Jung RE, Schneider D, Cochran DL, Ender A, Jones AA, Görlach C, Uebersax L, Graf‐Hausner U, Hämmerle CHF. Soft tissue volume augmentation by the use of collagen‐based matrices: a volumetric analysis. J Clin Peridontol 2010; 37: 659–666. doi: 10.1111/j.1600‐051X.2010.01581.x. Abstract Objectives: The aim was to test whether or not soft tissue augmentation with a newly developed collagen matrix (CM) leads to volume gain in chronic ridge defects similar to those obtained by an autogenous subepithelial connective tissue graft (SCTG). Material and Methods: In six dogs, soft tissue volume augmentation was performed by randomly allocating three treatment modalities to chronic ridge defects (CM, SCTG, sham‐operated control). Impressions were taken before augmentation (baseline), at 28, and 84 days. The obtained casts were optically scanned and the images were digitally analysed. A defined region of interest was measured in all sites and the volume differences between the time points were calculated. Results: The mean volume differences per area between baseline and 28 days amounted to a gain of 1.6 mm (CM; SD±0.9), 1.5 mm (SCTG; ±0.1), and a loss of 0.003 mm (control; ±0.3). At 84 days, the mean volume differences per area to baseline measured a gain of 1.4 mm (CM; ±1.1), 1.4 mm (SCTG; ±0.4), and a loss of 0.3 mm (control; ±0.3). The differences between CM and SCTG were statistically significant compared with control at 28 and 84 days ( p <0.001). Conclusion: Within the limits of this animal study, the CM may serve as a replacement for autogenous connective tissue.