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The influence of a probiotic milk drink on the development of gingivitis: a pilot study
Author(s) -
Staab Benedict,
Eick Sigrun,
Knöfler Gerhild,
Jentsch Holger
Publication year - 2009
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2009.01459.x
Subject(s) - gingivitis , probiotic , food science , dentistry , medicine , biology , bacteria , genetics
Aim: The aim of this study was to determine the effect of a probiotic milk drink on gingival health and the development of experimental gingivitis. Material and Methods: Fifty volunteer students took part in a parallel‐designed non‐blinded study. The test group drank a probiotic drink once a day; the control group did not receive any product to drink. After 8 weeks, individual mechanical plaque control was interrupted for 96 h. Papilla bleeding index, interproximal plaque and Turesky plaque index (PI) were recorded at baseline, after 8 weeks and again 96 h later. At the same time points, gingival crevicular fluid had been collected for analysis of polymorphonuclear elastase, myeloperoxidase (MPO) and matrix metalloproteinase‐3 (MMP‐3). Results: Interproximal PI and papillary bleeding were not different between the groups. In the test group, elastase activity and MMP‐3 amount were significantly lower after the intake of the probiotic milk drink ( p <0.001 and 0.016). There was a significant increase of MPO activity in the control group; both groups were different at the end of the study ( p =0.014). Conclusions: The data suggest a beneficial effect of the probiotic milk drink on gingival inflammation.