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Early healing of implants placed into fresh extraction sockets: an experimental study in the beagle dog. De novo bone formation
Author(s) -
Vignoletti Fabio,
Johansson Carina,
Albrektsson Tomas,
De Sanctis Massimo,
San Roman Fidel,
Sanz Mariano
Publication year - 2009
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2008.01363.x
Subject(s) - osseointegration , beagle , premolar , dentistry , implant , medicine , bone resorption , bone healing , bone formation , resorption , surgery , pathology , molar , endocrinology
Objectives: Describe the early phases of tissue integration in implants placed into fresh extraction sockets and test whether a new implant surface nano‐topography (DCD nano‐particles, Nanotite ™ ) promotes early osseointegration when compared with minimally rough surface implants (DAE, Osseotite ® ). Material and Methods: Sixteen beagle dogs received 64 test and control implants randomly installed into the distal socket of 3 P 3 and 4 P 4 . Histomorphometric analysis of bone to implant contact (BIC) and bone area was performed at 4 h, 1, 2, 4 and 8 weeks. Results: Wound healing initiated with a coagulum that was substituted by a provisional matrix at 1 week. Bone formation started concomitant to a marked bone resorption. At 2 weeks, woven bone formation was evident and gradually remodelled into lamellar bone at 4 and 8 weeks. BIC increased similarly throughout the study in both groups with a tendency to higher percentages for the test devices at 2 and 4 weeks. The influence of the DCD nano‐particles was more evident at the fourth premolar site. Conclusion: Osseointegration occurred similarly at both implant groups, although the socket dimension appeared to influence bone healing. It is suggested that the enhanced nano‐topography has a limited effect in the immediate implant surgical protocol.