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Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study
Author(s) -
Jones Judith A.,
Miller Donald R.,
Wehler Carolyn J.,
Rich Sharron E.,
KrallKaye Elizabeth A.,
McCoy Linda C.,
Christiansen Cindy L.,
Rothendler James A.,
Garcia Raul I.
Publication year - 2007
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2006.01002.x
Subject(s) - glycemic , medicine , diabetes mellitus , veterans affairs , confidence interval , odds ratio , randomized controlled trial , logistic regression , insulin , endocrinology
Objectives: Report results of a randomized‐clinical trial of the efficacy of periodontal care in the improvement of glycemic control in 165 veterans with poorly controlled diabetes over 4 months. Methods: Outcomes were change in Haemoglobin A1c (HbA1c) in the Early Treatment versus untreated (Usual Care) groups and percent of participants with decreases in HbA1c. Analyses included simple/multiple variable linear/logistic regressions, adjusted for baseline HbA1c, age, and duration of diabetes. Results: Unadjusted analyses showed no differences between groups. After adjustment for baseline HbA1c, age, and diabetes duration, the mean absolute HbA1c change in the Early Treatment group was −0.65% versus −0.51% in the Usual Care group ( p =0.47). Adjusted odds for improvement by 0.5% in the Early Treatment group was 1.67 (95% confidence interval: 0.84, 3.34, p =0.14). Usual Care subjects were twice as likely to increase insulin from baseline to 4 months (20% versus 11%, p =0.12) and less likely to decrease insulin (1% versus 6%, p =0.21) than Early Treatment subjects. Among insulin users at baseline, more increased insulin in the Usual Care group (40% versus 21%, p =0.06). Conclusions: No significant benefit was found for periodontal therapy after 4 months in this study; trends in some results were in favour of periodontal treatment.