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A review of the effects of stannous fluoride on gingivitis
Author(s) -
Paraskevas S.,
Van Der Weijden G. A.
Publication year - 2006
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2005.00860.x
Subject(s) - gingivitis , dentifrice , medicine , dentistry , meta analysis , dental plaque , fluoride , orthodontics , chemistry , inorganic chemistry
Aim: To review the literature on the effects of stannous fluoride on gingivitis. Material and Methods: The Medline and cochrane central register of controlled trials were searched up to August 2005 to identify appropriate studies. The primary outcome measure was gingivitis. Results: Independent screening of titles and abstracts of 542 papers resulted in 36 publications (inter‐reviewer ê score of 0.76), out of which 15 papers finally fulfilled the criteria of eligibility. For SnF 2 dentifrices , a statistically significant reduction in gingivitis was noted in comparison with control (weighted mean difference (WMD) of 0.15 (gingival index) and 0.21 (gingivitis severity index) (test for heterogeneity p <0.00001, I 2 =91.1% and p =0.03, I 2 =80.1%, respectively)). With regard to plaque reduction inconsistent results existed. On using the plaque index no differences were found, whereas meta‐analysis of the Turesky index provided a WMD of 0.31 ( p =0.01, test for heterogeneity p <0.0001, I 2 =91.7%). Because of insufficient data, a meta‐analysis for SnF 2 mouth rinse and dentifrice/mouthrinse formulations was not performed. Conclusions: The use of SnF 2 dentifrices results in gingivitis and plaque reduction when compared with a conventional dentifrice. The precise magnitude of this effect was difficult to assess because of a high level of heterogeneity in study outcomes.