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The association of gingivitis and periodontitis with ischemic stroke
Author(s) -
Dörfer Christof E.,
Becher Heiko,
Ziegler Christoph M.,
Kaiser Claudia,
Lutz Rainer,
Jörß Daniela,
Lichy Christoph,
Buggle Florian,
Bültmann Stefan,
Preusch Michael,
Grau Armin J.
Publication year - 2004
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.2004.00579.x
Subject(s) - medicine , periodontitis , gingivitis , clinical attachment loss , dentistry , ischemia , periodontium , exacerbation , stroke (engine) , population , risk factor , confidence interval , periodontal examination , mechanical engineering , environmental health , engineering
Objectives: The aim of this study was to assess the associations of different periodontal parameters with cerebral ischemia. Methods: In a case–control study, 303 consecutive patients with ischemic stroke or transient ischemic attack, and 300 representative population controls received a complete clinical and radiographic dental examination. Patients were examined on average 3 days after ischemia. The individual mean clinical attachment loss measured at four sites per tooth was used as indicator variable for periodontitis. Results: Patients had higher clinical attachment loss than population ( p <0.001). After adjustment for age, gender, number of teeth, vascular risk factors and diseases, childhood and adult socioeconomic conditions and lifestyle factors, a mean clinical attachment loss >6 mm had a 7.4 times (95% confidence interval 1.55–15.3) a gingival index >1.2 a 18.3 times (5.84–57.26) and a radiographic bone loss a 3.6 times (1.58–8.28) higher risk of cerebral ischemia than subjects without periodontitis or gingivitis, respectively. Conclusion: Periodontitis is an independent risk factor for cerebral ischemia and acute exacerbation of inflammatory processes in the periodontium might be a trigger for the event of cerebral ischemia.