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Salivary peroxidase activity in whole saliva of patients with insulin‐dependent (type‐1) diabetes mellitus
Author(s) -
Güven Y.,
Satman I.,
Dinççaǧ N.,
Alptekin S.
Publication year - 1996
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1996.tb00627.x
Subject(s) - saliva , medicine , diabetes mellitus , insulin , peroxidase , type 2 diabetes mellitus , endocrinology , biology , biochemistry , enzyme
In this study, salivary peroxidase activity was measured in a group of 10 patients with insulin‐dependent (type I) diabetes mellitus (IDDM) who had a tendency towards periodontitis. In healthy subjects ( N : 10), mean salivary peroxidase activity was 0.0025±0.001 IU/ml, while in this group of type I diabetic patients it was 0.051±0.015 IU/ml, a significantly higher level ( p <0.001). Approximal plaque index (API), modified sulcus bleeding index (mod SBI) and pocket depths were assessed clinically. The values for mod SBI and API were 60% and 68% respectively for the diabetic patients while for the control group mod SBI was measured 0.0% and the value for API was 10.67% ( p < 0.001). The administration of this simple and practical test may provide an early marker of a tendency towards periodontitis in IDDM patients.