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Collagen gel and membrane in guided tissue regeneration in periodontal fenestration defects in dogs
Author(s) -
Tal Haim,
Pitaru Sandu,
Moses Ofer,
Kozlovsky Avital
Publication year - 1996
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1996.tb00496.x
Subject(s) - cementum , regeneration (biology) , dental alveolus , fenestration , dentistry , dental cementum , membrane , biomedical engineering , anatomy , chemistry , dentin , medicine , surgery , biology , microbiology and biotechnology , biochemistry
The effect of a collagen gel matrix as a submembranous space‐maintaining material was evaluated in guided tissue regeneration procedures. In 4 dogs, contralateral surgical circular fenestration defects, 5 mm in diameter, were produced at the midbuccal aspect of the alveolar bone in 8 maxillary canines. Removal of bone, PDL and cementum was complete. Experimental sites were filled with collagen gel and covered with collagen membranes; control sites were covered with collagen membranes and the underlying space was spontaneously filled with blood. Mucogingival flaps were repositioned. Histological and histomorphometric observations, 6 weeks post‐surgery, indicated that defects covered by collagen membranes presented the most impressive regeneration with almost complete coverage of the denuded root by new cementum (98.4%) and new bone (63.2%). In the experimental defects. 83.5% coverage of new cementum with only 21.9% new bone regeneration was observed. These results suggest that collagen gel. interfered with healing by PDL and bone‐derived cells in the submembranous space.