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Evaluation of a mouthrinse containing chlorhexidine and fluoride as an adjunct to oral hygiene
Author(s) -
Jenkins S.,
Addy M.,
Newcombe R.
Publication year - 1993
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1993.tb01754.x
Subject(s) - chlorhexidine , medicine , gingivitis , dentistry , oral hygiene , fluoride , chlorhexidine gluconate , dental plaque , hygiene , chemistry , inorganic chemistry , pathology
Chlorhexidine and fluoride have valuable preventive roles in dental and oral diseases. There is also evidence that in caries prevention, together, they provide additive benefits. However, combined chlorhexidine/fluoride formulations have rarely been evaluated. The aim of this study was to determine whehter a 0.12% chlorhexidine, 100 ppm F‐ mouthrinse provided adjunctive oral hygiene benefits compared to a minus active control rinse. The study was a randomised double‐blind parallel design involving 102 subjects of whom 99 completed the 6 week experimental period. Subjects rinsed 2 × per day for 1 min with 15 ml of the allocated rinse. Normal toothbrushing procedures were maintained throughout the study. At 6 weeks, plaque and gingivitis scores were significantly lower and the incremental reduction significantly larger in the active rinse group. However, as expected, tooths mining was significantly increased with the active rinse. It is apparent that this chlorhexidine/fluoride rinse could be used in those regimens recommended for other chlorhexidine formulations. The value of the formulation in caries prevention would seem worthy of further investigation.