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The survival of subgingival plaque bacteria in an amine fluoride‐containing gel
Author(s) -
Bansal G. S.,
Newman H. N.,
Wilson M.
Publication year - 1990
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1990.tb02339.x
Subject(s) - microbiology and biotechnology , bacteria , periodontal disease , dental plaque , bacteroides , chemistry , biology , medicine , dentistry , genetics
. Subgingival plaque samples from 20 patients with chronic inflammatory periodontal disease were exposed to a commercial gel formulation containing 2 amine fluorides. The MIC of the gel for these samples ranged from 33 to 260 μ/ml with a modal value of 260 μ/ml. In each sample, the most resistant organisms (i.e., those organisms surviving at one doubling dilution below the MIC) were identified. 33 such organisms were isolated, of which 22 (67%) were strict anaerobes, and 25 (75%) were Gram negative. The 2 most frequent isolates were Bacteroides ruminicola ss. brevis and a Selenomonas species, neither of which is a recognised periodontopathogen. The gel had a rapid effect on the viability of the bacteria in the plaque samples, the 90% kill time being 17 min or less for 90% of the samples (range <5 to 71 min).