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Antimicrobial properties of 2 aliphatic amines and chlorhexidine in vitro and in saliva
Author(s) -
Salem A. M.,
Adams D.,
Newman H. N.,
Rawle L. W.
Publication year - 1987
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1987.tb01512.x
Subject(s) - chlorhexidine , saliva , antimicrobial , microbiology and biotechnology , bacteria , chemistry , bacterial growth , antibacterial activity , streptococcus mutans , in vitro , serial dilution , dental plaque , dentistry , biology , medicine , biochemistry , genetics , alternative medicine , pathology
The surfactants tetradecylamine, hexadecylamine and chlorhexidine have been compared with regard to their ability to inhibit microbial growth. Antibacterial activity was assessed by tube dilution methods. Tetradecylamine and chlorhexidine were similar in antibacterial activity, being effective at low concentrations against most organisms tested. Hexadecylamine also inhibited growth but at higher concentrations. Viable counts of salivary organisms were monitored in volunteers over 48 h after one rinse with the agents. The initial reduction in numbers of total viable salivary bacteria and streptococci by tetradecylamine and of streptococci by hexadecylamine had disappeared 3 h after a single mouth rinse, but the reduction in numbers of all salivary bacteria by chlorhexidine was more prolonged.