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Experimental gingivitis in relation to age in individuals not susceptible to periodontal destruction
Author(s) -
Winkel E. G.,
Abbas F.,
Velden U.,
Vroom Th. M.,
Scholte G.,
Hart A. A. M.
Publication year - 1987
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1987.tb00990.x
Subject(s) - gingivitis , gingival inflammation , medicine , interdental consonant , dentistry , oral hygiene , periodontitis , clinical attachment loss , dental plaque , age groups , pathology , demography , sociology
The purpose of the present investigation was to study the effect of age on the rate of development of gingival inflammation in individuals not susceptible to periodontal destruction. 7 younger (mean age 37 years) and 7 older (mean age 58 years) individuals were selected on the basis of the presence of at least 18 teeth, no evidence of extraction due to periodontal destruction, no loss of attachment, shallow pockets, gross amounts of plaque and a history of no interdental cleaning. All individuals were subjected to a carefully controlled oral hygiene program and experimental gingivitis was induced in 1 quadrant of the mouth during a period of 33 days. The amount of plaque, redness and swelling of the gingivitis, and bleeding on probing were assessed before, during and after the experiment. Al day 33, supra‐gingival plaque samples were taken for bacteriological examination and gingival biopsies were taken for histopathological and immunohistochemical investigation. Results showed no differences between the 2 age groups with regard to the amount of plaque accumulation and the rate of development of gingival inflammation. Furthermore phase‐contrast microscopy of plaque samples showed no differences between the 2 age groups. Neither his to‐logical nor immunohistochemical investigation showed any differences between the 2 age groups. All biopsies diffusely showed presence of IgG, whereas in most biopsies, IgA plasma cells and in one biopsy IgM plasma cells were found. Neither IgD, IgE nor complement deposits were found. It was concluded that age is of minor importance in the development of experimentally‐induced gingivitis in individuals not susceptible to periodontal destruction.