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Association between bacteriophage‐infected Actinobacillus action‐mycetemcomitans and rapid periodontal destruction
Author(s) -
Preus Hans R.,
Olsen Ingar,
Namork Ellen
Publication year - 1987
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1987.tb00974.x
Subject(s) - actinobacillus , bacteriophage , microbiology and biotechnology , medicine , action (physics) , biology , dentistry , periodontitis , escherichia coli , genetics , gene , physics , quantum mechanics
Actinobacillus actinomycetemcomitans was isolated from periodontal pockets in a patient suffering from prepubertal periodontitis. Electron microscopy revealed 3 different groups of bacteriophages in Filtrates of subgingival plaque from all the active periodontal lesions. Phage infected A. actinomycetemcomitans in this patient was restricted to periodontal pockets which, according to standardized roentgenograms, had shown bone destruction during the past 12 months. A follow‐up study of 7 months revealed that a “burned out” site which harbored noninfected A. actinomycetemcomitans , turned into an active site at the same time as the A. actinomycetemcomitans of that site became infected with the phages. These findings indicate a relationship between rapid prepubertal periodontal destruction and phage‐infected A. actinomycetemcomitans.