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Dynamics of infection by leukotoxic strains of actinobacillus actinomycetemcomitans in juvenile periodontitis
Author(s) -
Tsai ChiCheng,
Taichman Norton S.
Publication year - 1986
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1986.tb02231.x
Subject(s) - actinobacillus , periodontitis , juvenile , incidence (geometry) , medicine , microbiology and biotechnology , immunology , biology , dentistry , genetics , physics , optics
. Juvenile periodontitis is associated with a high incidence of infection by Actinobacillus aclinomycetemcomilans (Aa). The data presented indicate that the ability of Aa to destroy human PMNs is altered during the course of infection. Leukotoxic strains of Aa are characteristically found in isolates obtained from younger patients (6–12 years of age) but not in older subjects (13–25 years old). This suggests that the leukotoxin may be more important during early as opposed to more advanced phases of juvenile periodontitis.