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Cell populations associated with interdental gingival bleeding *
Author(s) -
Thilo B. E.,
Caton J. G.,
Poison A. M.,
Espeland M. A.
Publication year - 1986
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1986.tb02230.x
Subject(s) - medicine , connective tissue , gingivitis , interdental consonant , periodontitis , bleeding on probing , lesion , pathology , dentistry , periodontal disease , gingival disease , peripheral blood mononuclear cell , biology , in vitro , biochemistry
. The purpose of this study was to characterize the cell populations of the mid‐interproximal gingival tissue related to the presence or absence of bleeding. 15 bleeding and 15 non‐bleeding interproximal gingival biopsies were obtained from 30 patients and processed for light microscopic evaluation. Morphometric analysis of tissue components revealed that bleeding was associated with an inflammatory lesion located in the mid‐interproximal connective tissue. The inflammatory infiltrate was dominated by mononuclear cells of the lymphocyte/macrophage/monocyte group, and the proportions of plasma cells and polymor‐phonuclear leukocytes were relatively small. The results of this study indicated that interproximal bleeding can be associated with an inflammatory infiltrate not dominated by plasma cells. The rôle of gingival bleeding in the diagnosis of periodontal disease activity is discussed.