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Treatment of the periodontal component of Papillon‐Lefèvre syndrome
Author(s) -
Tinanoff Norman,
Tanzer Jason M.,
Kornman Kenneth S.,
Maderazo Eufronio G.
Publication year - 1986
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1986.tb01407.x
Subject(s) - medicine , periodontal disease , gingival and periodontal pocket , dentistry , hyperkeratosis , gingivitis , polymorphonuclear leukocyte , dermatology , biology , biochemistry , in vitro
A 9‐year‐old girl was treated for the periodontal component of Papillon‐Lefevre syndrome, an autosomal recessive disease characterized by palmar‐plantar hyperkeratosis and premature loss of teeth. Initially, the patient was found to have a polymorphonuclear leukocyte chemotactic dysfunction, defective leukocyte adherence, and deep periodontal pockets harboring presumptive periodontopathic bacteria. After unsuccessful treatment with combined mechanical therapy and 2 different antibiotics, all of the patient's erupted teeth were extracted in an attempt to minimize the chance of infection of teeth yet to erupt. At age 16 years, the now‐erupted teeth have normal gingiva and crevice depths, radiographs show no evidence of periodontal pathology, no periodontopathic bacteria are detected in gingival crevices, and leukocyte function is normal.