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Efficacy of Listerine antiseptic in inhibiting the development of plaque and gingivitis
Author(s) -
Gordon J. M.,
Lamster I. B.,
Seiger M. C.
Publication year - 1985
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1985.tb00941.x
Subject(s) - gingivitis , antiseptic , medicine , dentistry , oral hygiene , dental plaque , dental prophylaxis , stain , staining , pathology
A 9‐month double‐blind controlled clinical study was conducted on adult subjects using either Listerine antiseptic, its vehicle control, or a water control in order to determine the efficacy of the antiseptic mouth rinse in inhibiting the development of plaque and gingivitis. Following screening examinations for minimal entry levels of plaque and gingivitis, all subjects received a complete prophylaxis. Subjects then continued their usual oral hygiene habits for a 3‐week normalization period and were examined for soft tissue abnormalities and baseline measurements of plaque, gingivitis, and tooth stain. 2 additional prophylaxes were then performed, followed by a second baseline gingival examination. Zero plaque was re‐established by rubber cup polishing and twice daily rinsing was begun. Soft tissue, plaque, gingivitis, and extrinsic tooth stain were evaluated after 1, 3. 6 and 9 months of rinsing with the randomly assigned mouthrinses. Results demonstrated that Listerine antiseptic significantly reduced the development of plaque at 1,3.6 and 9 months and the development of gingivitis at 9 months, as compared to its vehicle control or water control.

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