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Comparison of the effect of chlorhexidine and CuSO 4 on plaque formation and development of gingivitis
Author(s) -
Waerhaug Marthe,
Gjermo Per,
R∅oslla Gunnar,
Johansen Jan R.
Publication year - 1984
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1984.tb01321.x
Subject(s) - gingivitis , chlorhexidine , dentistry , dental plaque , oral hygiene , medicine , chemistry
Recent studies have shown that several metal ions inhibit plaque formation and reduce the acidogenicity of dental plaque. The aim of the present study was to compare the effect on plaque and gingivitis of 2.2 mM CuSO 4 with an equimolar solution of chlorhexidine in a modified experimental gingivitis model. The study was performed according to a double‐blind cross‐over design. Before each experimental period the GI was recorded and the participants’ teeth were scaled and polished to remove all supragingivul deposits. All mechanical oral hygiene was suspended during the experimental periods. The mean PlI after rinsing with chlorhexidine, CuSO 4 and water was 0.29, 0.79 and 1.25, respectively. The corresponding GI values were 0.57, 0.83 and 1.02. All differences were statistically significant. The results showed that CuSO 4 inhibits plaque formation and development of gingivitis, but not to the same degree as chlorhexidine.