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Periodontal status associated with chronic neutropenia
Author(s) -
Baehni Pierre C.,
Payot Pierre,
Tsai ChiCheng,
Cimasoni Giorgio
Publication year - 1983
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1983.tb02209.x
Subject(s) - actinobacillus , neutropenia , medicine , etiology , pathogenesis , dental alveolus , inflammation , immunology , antibody , disease , periodontitis , dentistry , chemotherapy
. A case of chronic neutropenia in a 12‐year‐old boy is reported. The patient presented with severe gingival inflammation and alveolar bone loss, Immunologic analysis of the patient's serum revealed the presence of precipitating antibodies against antigenic components of Actinobacillus actinamycetemcomitans Y4 and 652. It was also found that the serum neutralized the leukotoxicactivity of Actinobacillus actinomycetemcomtians Y4. The etiology and the pathogenesis of periociontal disease in neutropenic patients are discussed in view of these findings.