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Outlook for Hibitane in dental caries
Author(s) -
Emilson C. G.
Publication year - 1977
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1977.tb00060.x
Subject(s) - chlorhexidine , streptococcus mutans , medicine , dentistry , antimicrobial , oral cavity , dental plaque , drug , microbiology and biotechnology , pharmacology , biology , bacteria , genetics
The association between S. mutans and dental caries in humans has focused the interest on the possibility to suppress or eliminate this microorganism from the oral cavity, In this respect chlorhexidine seems to be a valuable adjunct, since S. mutans is highly sensitive to the drug. In hamsters and rats infected with S. mutans topical applications of chlorhexidine have been highly effective in lowering the caries activity. In long‐term studies in students, a certain caries inhibiting effect has also been demonstrated. The decrease in the prevalence of S. mutans by chlorhexidine treatment suggests that the drug can be used for directed and controlled antimicrobial therapy in subjects highly infected with S. mutans.