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Influence of two barrier membranes on staged guided bone regeneration and osseointegration of titanium implants in dogs. Part 2: augmentation using bone graft substitutes
Author(s) -
Mihatovic Ilja,
Becker Jürgen,
Golubovic Vladimir,
Hegewald Andrea,
Schwarz Frank
Publication year - 2012
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/j.1600-0501.2011.02238.x
Subject(s) - osseointegration , dentistry , barrier membrane , titanium , regeneration (biology) , medicine , membrane , implant , materials science , chemistry , surgery , biology , microbiology and biotechnology , biochemistry , metallurgy
Objectives: To assess the influence of two barrier membranes and two bone graft substitutes on staged guided bone regeneration and osseointegration of titanium implants in dogs.Materials and methods: Saddle‐type defects were prepared in the lower jaws of 6 fox hounds and randomly filled with a natural bone mineral (NBM) and a biphasic calcium phosphate (SBC) and allocated to either an in situ gelling polyethylene glycol (PEG) or a collagen membrane (CM). At 8 weeks, modSLA titanium implants were inserted and left to heal in a submerged position. At 8+2 weeks, respectively, dissected blocks were processed for histomorphometrical analysis (e.g., mineralized tissue [MT], bone‐to‐implant contact [BIC]).Results: The mean MT values (mm 2 ) and BIC values (%) tended to be higher in the PEG groups (MT: NBM [3.4±1.7]; SBC [4.2±2]/BIC: NBM [67.7±16.9]; SBC [66.9±17.8]) when compared with the corresponding CM groups (MT: NBM [2.5±0.8]; SBC [2.3±1.6]/BIC: NBM [54.1±22.6]; SBC [61±8.7]). These differences, however, did not reach statistical significance.Conclusion: It was concluded that all augmentation procedures investigated supported bone regeneration and staged osseointegration of modSLA titanium implants.To cite this article :
Mihatovic I, Becker J, Golubovic V, Hegewald A, Schwarz F. Influence of two barrier membranes on staged guided bone regeneration and osseointegration of titanium implants in dogs. Part 2: augmentation using bone graft substitutes.
Clin Oral Impl Res . 23 , 2012; 308–315.
doi: 10.1111/j.1600‐0501.2011.02238.x