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Retracted: Bone response to hydroxyapatites with open porosity of animal origin (porcine [OsteoBiol ® mp3] and bovine [Endobon ® ]): a radiological and histomorphometric study
Author(s) -
RamírezFernández MaPiedad,
CalvoGuirado Jose Luis,
DelgadoRuiz Rafael Arcesio,
MatéSánchez del Val José Eduardo,
VicenteOrtega Vicente,
MeseguerOlmos Luis
Publication year - 2011
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/j.1600-0501.2010.02058.x
Subject(s) - hydroxyapatites , radiological weapon , porosity , dentistry , nuclear medicine , radiochemistry , chemistry , medicine , calcium , organic chemistry
Purpose: To carry out a radiological and histomorphometric evaluation of bone response to two xenografts of animal origin, one porcine, and the other bovine, inserted in rabbits' tibiae. Material and methods: Twenty New Zealand rabbits weighing 3900–4500 g were used. Twenty bovine bone grafts (Endobon ® ) in granulated form of 500–1000 μm granulometry were inserted in the proximal metaphyseal area of the animals' right tibia, and 20 porcine bone grafts (OsteoBiol ® mp3) in granulated form of 600–1000 μm granulometry were inserted in the proximal metaphyseal area of the animals' left tibia. Following graft insertion, the animals were sacrificed in four groups of five, after 1, 2, 3 and 4 months, respectively. Anteroposterior and lateral radiographs were taken. Samples were processed for observation under light microscopy. Histomorphometric measurements were presented as mean values ± standard deviations. Results: At 4 months after treatment, the bone defects displayed radiological images that showed complete repair of osseous defects. Histomorphometric evaluation showed that for the porcine xenograft, the study averages for newly formed bone represented 22.8 ± 1.8%, for residual graft material 23.6 ± 3% and for connective tissue 53.5 ± 2.5%, while for the bovine xenograft newly formed bone represented 23.1 ± 1.8%, residual graft material 39.4 ± 3% and non‐mineralized connective tissue 37.5 ± 2.5%. Conclusions: The biomaterials assessed in the study were shown to be biocompatible and osteoconductive. Collagenized porcine xenografts proved more resorbable than bovine xenografts. Both can be used as possible bone substitutes without interfering with normal reparative bone processes. To cite this article:
Ramírez‐Fernández MP, Calvo‐Guirado JL, Delgado‐Ruiz RA, Maté‐Sánchez del Val JE, Vicente‐Ortega V, Meseguer‐Olmos L. Bone response to hydroxyapatites with open porosity of animal origin (porcine [OsteoBiol ® mp3] and bovine [Endobon ® ]): a radiological and histomorphometric study.
Clin. Oral Impl. Res . 22 , 2011; 767–773.
doi: 10.1111/j.1600‐0501.2010.02058.x