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Atrophic maxillary floor augmentation by mineralized human bone allograft in sinuses of different size: an histologic and histomorphometric analysis
Author(s) -
Maria Soardi Carlo,
Spinato Sergio,
Zaffe Davide,
Wang HomLay
Publication year - 2011
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1111/j.1600-0501.2010.02034.x
Subject(s) - maxillary sinus , medicine , cancellous bone , dentistry , sinus (botany) , cortical bone , histology , maxilla , osseointegration , biopsy , implant , anatomy , surgery , pathology , botany , biology , genus
Objective: The aims of this work were to histologically examine the healing of mineralized human bone allograft (MHBA) in sinus augmentation for elevating a severe maxillary atrophy ridge (≤2 mm residual ridge height) and to correlate the results to the sinus cavity size. Material and methods: A two‐stage protocol was conducted in 23 patients, all having crestal bone ≤2 mm. A mixture of 80/20 cortical/cancellous of MHBA particles was used to augment sinus using the lateral window approach in narrow (NS; <15 mm bucco‐palatal distance) and wide (WS; ≥15 mm bucco‐palatal distance) sinuses, based upon computerized tomography (CT) assessment. A bone core biopsy was taken at implant placement, 6 and 9 months after surgery. Microradiography, histology and histochemistry of methacrylate‐embedded sections were performed to analyze and to evaluate the bone and graft amount. Results: Newly formed bone around MBHA particles was found in all 28 biopsies. Bone showed a woven structure at 6 months after surgery and a lamellar structure 9 months after surgery. At 6 months after surgery, the 13 NS and 15 WS had 30.5±8.8% and 20.7±4.9% mean±SD bone formation, respectively. At 9 months after surgery, it was 38.8±7% (NS) and 30.7±3% (WS). Residual graft was about 16% (6 months) and 6% (9 months), in both NS and WS. The Mann–Whitney test showed a greater bone formation in NS than in WS ( P <0.005). Conclusions: The used 80/20 MHBA mixture appears to promote, in the severe atrophic maxilla, a satisfactory bone formation. Our results prove that the larger the sinus, the longer the maturation time needed to achieve a suitable amount of new bone formation. To cite this article:
Maria Soardi C, Spinato S, Zaffe D, Wang H‐L. Atrophic maxillary floor augmentation by mineralized human bone allograft in sinuses of different size: an histologic and histomorphometric analysis.
Clin. Oral Impl. Res . 22 , 2011; 560–566
doi: 10.1111/j.1600‐0501.2010.02034.x