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Presence of arginine catabolic mobile element among community‐acquired meticillin‐resistant staphylococcus aureus is linked to a specific genetic background
Author(s) -
Hedlund Linda,
Hellmark Bengt,
Söderquist Bo
Publication year - 2013
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1600-0463.2012.02959.x
Subject(s) - staphylococcus aureus , pulsed field gel electrophoresis , microbiology and biotechnology , leukocidin , mobile genetic elements , colonization , methicillin resistant staphylococcus aureus , staphylococcal infections , panton–valentine leukocidin , biology , meticillin , micrococcaceae , medicine , bacteria , genotype , genetics , gene , genome
The prevalence of arginine catabolic mobile element ( ACME ) among diverse and heterogeneous community‐associated methicillin‐resistant Staphylococcus aureus community‐associated Methicillin‐resistant S. aureus ( CA ‐ MRSA ) (n = 114) in a low‐endemic area, i.e. Sweden, was investigated. Among the CA ‐ MRSA , represented by 47 different spa types, ACME was only found in 10 isolates with a common genetic background [t008, SCC mec type IV , Panton‐Valentine leukocidin ( PVL ) positive, and indistinguishable or closely related pulsed‐field gel electrophoresis ( PFGE )‐patterns] corresponding to USA300. This strain does not seem to be established in our area as most of the patients contracted the CA ‐ MRSA abroad. Presence of ACME does not seem to be associated with colonization, long‐term carriership, or intra‐familiar transmission in a higher extent than CA ‐ MRSA in general.