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Antibiotic susceptibility in prostate‐derived Propionibacterium acnes isolates
Author(s) -
Olsson Jan,
Davidsson Sabina,
Unemo Magnus,
Mölling Paula,
Andersson SwenOlov,
Andrén Ove,
Söderquist Bo,
Sellin Mats,
Elgh Fredrik
Publication year - 2012
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1600-0463.2012.02905.x
Subject(s) - propionibacterium acnes , antibiotics , microbiology and biotechnology , medicine , biology , dermatology , acne
The aim of this study was to determine antibiotic susceptibility of Propionibacterium acnes isolates from prostate. Prostate‐derived P. acnes isolates (n = 24, Umeå & Örebro, Sweden, 2007–2010) and a panel of control strains (n = 25, Sweden) collected from skin and deep infections were assessed for resistance to penicillin G, piperacillin–tazobactam, imipenem, gentamicin, azithromycin, erythromycin, vancomycin, ciprofloxacin, moxifloxacin, tetracycline, tigecycline, fusidic acid, clindamycin, rifampicin, linezolid, daptomycin, trimethoprim–sulfamethoxazole, and metronidazole. In addition, the isolates were tested for inducible clindamycin resistance. All prostate derived P. acnes isolates displayed wild‐type distribution of MIC ‐values, without evidence of acquired resistance. In the reference panel, 5 of 25 isolates had acquired macrolide resistance with cross‐resistance to azithromycin, clindamycin, and erythromycin. In addition, one of these isolates was resistant to tetracycline.