Premium
Comparison of IgG avidity assays in the confirmation of the diagnosis of cytomegalovirus primary infection
Author(s) -
GUISASOLA MARÍA EULALIA,
RAMOS BELÉn,
SANZ JUAN CARLOS,
GARCÍABERMEJO ISABEL,
DE ORY MANCHÓN FERNANDO
Publication year - 2010
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1600-0463.2010.02682.x
Subject(s) - avidity , cytomegalovirus , immunoassay , virology , chemiluminescent immunoassay , immunology , antibody , cytomegalovirus infections , immunoglobulin g , human cytomegalovirus , medicine , herpesviridae , virus , viral disease
Guisasola ME, Ramos B, Sanz JC, García‐Bermejo I, de Ory Manchón F. Comparison of IgG avidity assays in the confirmation of the diagnosis of cytomegalovirus primary infection. APMIS 2010; 118: 991–3. We have compared three ELISA techniques and one chemiluminescence immunoassay technique for determining cytomegalovirus (CMV) immunoglobulin G (IgG) avidity in serum samples from patients with recent and past CMV infections. Sensitivity varied from 84.6% to 100%; and specificity from 78.6% to 100%. IgG avidity assays appear to be adequate additional tools for characterizing CMV infections.