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The spectrum of vascular involvement in giant‐cell arteritis: clinical consequences of detrimental vascular remodelling at different sites
Author(s) -
CID MARIA C.,
PRIETOGONZÁLEZ SERGIO,
ARGUIS PEDRO,
ESPÍGOLFRIGOLÉ GEORGINA,
BUTJOSA MONTSERRAT,
HERNÁNDEZRODRÍGUEZ JOSÉ,
SEGARRA MARTA,
LOZANO ESTER,
GARCÍAMARTÍNEZ ANA
Publication year - 2009
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1600-0463.2009.02471.x
Subject(s) - giant cell arteritis , vascular remodelling in the embryo , arteritis , broad spectrum , medicine , vascular disease , pathology , vasculitis , disease , combinatorial chemistry , chemistry
Although repeatedly reported in the literature, the extracranial involvement by giant‐cell arteritis has been considered anecdotal until recent years. The emergence of new or improved imaging techniques along with a closer follow‐up of these patients and their increase in life expectancy are beginning to underline that the clinical impact of extracranial involvement by GCA may be more relevant than previously thought. This review focuses on the extent of vascular involvement in GCA as reported by pathology and imaging studies as well as the clinical consequences of imperfect vascular remodelling in various vascular territories.