T‐cell/histiocyte‐rich large B‐cell lymphoma associated with a near‐tetraploid karyotype and complex genetic abnormalities | Zendy

DE LEVAL LAURENCE | Zendy; HARRIS NANCY LEE | Zendy; LAMPERTZ SERGE | Zendy; HERENS CHRISTIAN | Zendy

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T‐cell/histiocyte‐rich large B‐cell lymphoma associated with a near‐tetraploid karyotype and complex genetic abnormalities

Author(s) -

DE LEVAL LAURENCE,

HARRIS NANCY LEE,

LAMPERTZ SERGE,

HERENS CHRISTIAN

Publication year - 2006

Publication title -

apmis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.909

H-Index - 88

eISSN - 1600-0463

pISSN - 0903-4641

DOI - 10.1111/j.1600-0463.2006.apm_458.x

Subject(s) - bcl6 , karyotype , histiocyte , lymphoma , biology , pathology , cytogenetics , chromosome , b cell , genetics , medicine , immunology , gene , germinal center , antibody

Cytogenetic data for T‐cell/histiocyte‐rich large B‐cell lymphoma (THRLBCL) are scarcely available. We report here a case of THRLBCL with a near‐tetraploid karyotype and complex chromosomal aberrations, without rearrangement of BCL2 or BCL6, and characterized pathologically by a variegated morphologic appearance with areas resembling nodular lymphocyte‐predominant Hodgkin's lymphoma (NLPHL).

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