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Carcinosarcoma of the parotid gland: an unusual case with large‐cell neuroendocrine carcinoma and rhabdomyosarcoma
Author(s) -
UEO T.,
KAKU N.,
KASHIMA K.,
DAA T.,
KONDO Y.,
YOSHIDA K.,
SUZUKI M.,
YOKOYAMA S.
Publication year - 2005
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/j.1600-0463.2005.apm_231.x
Subject(s) - carcinosarcoma , parotid gland , rhabdomyosarcoma , pathology , pleomorphic adenoma , medicine , sarcoma , lymph node , spindle cell sarcoma , carcinoma ex pleomorphic adenoma , adenocarcinoma , carcinoma , parotidectomy , salivary gland , cancer
We report a case of carcinosarcoma of the parotid gland in a 72‐year‐old Japanese man. The patient noticed a rapidly enlarging hard mass in the right parotid gland. He underwent radical parotidectomy with cervical lymph node dissection. The resected tumor measured 3.5×4.5 cm and histopathologically showed carcinomatous and sarcomatous components. The carcinomatous component consisted of large‐cell neuroendocrine carcinoma (LCNEC), squamous cell carcinoma and adenocarcinoma not otherwise specified, while the sarcomatous component included spindle cell sarcoma not otherwise specified, so‐called myxosarcoma and rhabdomyosarcoma. The LCNEC component was predominant within the whole tumor. The diagnoses of LCNEC and rhabdomyosarcoma were also confirmed immunohistochemically. With regard to histopathogenesis, based on the lack of histopathological evidence and antecedent history of pleomorphic adenoma, we considered the present case to be de novo , not ex pleomorphic adenoma.