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Outcome of suicidal patients with schizophrenia: results from a naturalistic study
Author(s) -
SchennachWolff R.,
Jäger M.,
Seemüller F.,
Obermeier M.,
Schmauss M.,
Laux G.,
Pfeiffer H.,
Naber D.,
Schmidt L. G.,
Gaebel W.,
Klosterkötter J.,
Heuser I.,
Maier W.,
Lemke M. R.,
Rüther E.,
Klingberg S.,
Gastpar M.,
Möller H.J.,
Riedel M.
Publication year - 2010
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2009.01484.x
Subject(s) - hamd , schizophrenia (object oriented programming) , positive and negative syndrome scale , psychology , rating scale , medicine , psychiatry , depression (economics) , hamilton rating scale for depression , clinical psychology , psychosis , major depressive disorder , cognition , developmental psychology , economics , macroeconomics
Schennach‐Wolff R, Jäger M, Seemüller F, Obermeier M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller H‐J, Riedel M. Outcome of suicidal patients with schizophrenia: results from a naturalistic study. Objective: Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences. Method: Biweekly PANSS (Positive and Negative Syndrome Scale), HAMD (Hamilton Depression Rating Scale) and UKU (Udvalg for Klinske Undersogelser Side Effect Rating Scale) ratings were evaluated in 339 in‐patients with schizophrenic spectrum disorders. Response was defined as an initial 20% PANSS total score reduction at discharge, remission was defined according to the proposed consensus criteria by the Remission in Schizophrenia Working Group. Results: Suicidal patients (22%) scored significantly higher on the PANSS negative subscore, PANSS insight item and HAMD total score at admission and at discharge. They developed significantly more side effects. No differences were found concerning response and remission between the two patient subgroups. Conclusion: Despite receiving significantly more antidepressants the suicidal patients suffered from significantly more depressive symptoms up to discharge, yet without differing regarding response and remission.