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Preliminary results of a fine‐grain analysis of mood swings and treatment modalities of bipolar I and II patients using the daily prospective life‐chart‐methodology
Author(s) -
Born C.,
Seitz N.N.,
Grunze H.,
Vieta E.,
Dittmann S.,
Seemüller F.,
Amann B.
Publication year - 2009
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2009.01412.x
Subject(s) - hypomania , bipolar disorder , mania , mood swing , mood , bipolar ii disorder , depression (economics) , psychiatry , psychology , mood stabilizer , medicine , economics , macroeconomics
Objective: The study aimed to increase the knowledge about the detailed course differences between different forms of bipolar disorder. Method: Using the prospective life‐chart‐clinician version, we compared the fine‐grain analysis of mood swings and treatment modalities of 18 bipolar II with 31 bipolar I patients. Results: During an observational period of a mean of 26 months we observed an increase of euthymic days, and a decrease of (sub)depressive and (hypo)manic days. Days in a (sub)depressed state were more frequent than days of (hypo)mania as well as days of subdepression or hypomania in comparison to days of full‐blown depression or mania. Bipolar II patients showed an increase in hypomanic days receiving more frequently antidepressants. Bipolar I patients, with a decrease of manic days, were significantly taking more often mood stabilizers. Conclusion: Treatment in a specialized bipolar clinic improves the overall outcome, but bipolar II disorder seems to be still treated sub‐optimally with a possible iatrogenic increase of hypomanic days.