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Relapse rates in an early psychosis treatment service
Author(s) -
Addington D.,
Jean Addington M. D.,
Patten S.
Publication year - 2007
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2006.00879.x
Subject(s) - medicine , psychosis , cohort , censoring (clinical trials) , population , pediatrics , psychiatry , pathology , environmental health
Objective: To examine the relapse rate achievable in a real‐life early psychosis treatment service. Method: A 2‐year longitudinal cohort study of consecutive admissions to an early psychosis programme which served the entire population in a catchment area. The primary outcome measure was relapse. Results: One hundred and forty‐eight consecutive consenting admissions were recruited, 124 (83.8%) of whom were followed for 1 year and 116 (78.4%) for 2 years. Relapse was assessed by clinicians using structured criteria. The 2‐year relapse rate among subjects with complete data collection was 34/95 (35.7%, 95% CI 26.2–46.3). A Kaplan–Meier life table censoring subjects lost to follow‐up yielded a comparable estimate of the proportion not relapsing: 68% (95% CI 58–76%). Conclusion: These estimates compare favourably with a published range of 2‐year relapse from 55% to 70% in the older literature and are comparable with the results in recent clinical trials.