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CSF 5‐HIAA, suicide intent and hopelessness in the prediction of early suicide in male high‐risk suicide attempters
Author(s) -
Samuelsson M.,
Jokinen J.,
Nordström A.L.,
Nordström P.
Publication year - 2006
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2005.00639.x
Subject(s) - beck hopelessness scale , psychiatry , suicide attempt , medicine , suicide prevention , poison control , psychology , suicide risk , depression (economics) , clinical psychology , medical emergency , economics , macroeconomics
Objective: To study the predictive value of the Beck Suicide Intent Scale (SIS), the Beck Hopelessness Scale (BHS) and of 5‐hydroxyindoleacetic acid (5‐HIAA) in the cerebrospinal fluid for future early suicide in a group of high‐risk male suicide attempters. Method: Fifteen consecutive male suicide attempters admitted to a psychiatric ward at the Karolinska Hospital, who were not receiving any treatment with antidepressants were diagnosed according to DSM‐III, assessed with SIS and BHS and submitted to lumbar puncture. All patients were followed up for cause of death. Results: Five early suicides (within 2 years) were identified. Mean cerebrospinal fluid (CSF) 5‐HIAA differed between suicides and survivors. Low CSF 5‐HIAA was identified in those who committed early suicide. Neither the Suicide Intent Score nor the Hopelessness Score distinguished suicides from survivors. Conclusion: In high suicide risk hospitalized male psychiatric patients CSF 5‐HIAA may be a better predictor of early suicide after attempted suicide than SIS or BHS.