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Patterns of premorbid functioning in first episode psychosis: relationship to 2‐year outcome
Author(s) -
Addington J.,
Addington D.
Publication year - 2005
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2005.00511.x
Subject(s) - psychosis , psychology , depression (economics) , social functioning , psychiatry , clinical psychology , cognition , cognitive skill , verbal fluency test , schizophrenia (object oriented programming) , neuropsychology , distress , economics , macroeconomics
Objective: To determine how different patterns of premorbid functioning relate to outcome longitudinally. Method: Premorbid adjustment was assessed in 194 first‐episode of psychosis subjects. Positive and negative symptoms, depression, substance misuse and social and cognitive functioning were assessed over 2 years. Results: Four patterns of premorbid adjustment: stable‐good, stable‐intermediate, poor‐deteriorating and deteriorating were identified. Relative to the stable‐good group, the deteriorating and poor‐deteriorating groups had significantly more positive symptoms at 1‐year follow‐up but not at 2‐year follow‐up and significantly more negative symptoms and significantly poorer social functioning at both 1 and 2‐years. Only verbal fluency and memory differentiated between the groups with the stable‐good group having a superior performance. Conclusion: Those who demonstrated poor or deteriorating functioning prior to the onset of acute psychosis have a poorer outcome up to at least 2 years in terms of negative symptoms and social functioning.