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Predicting the onset of major depression in subjects with subthreshold depression in primary care: a prospective study
Author(s) -
Cuijpers P.,
Smit F.,
Willemse G.
Publication year - 2005
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2004.00416.x
Subject(s) - depression (economics) , subthreshold conduction , psychiatry , psychology , multivariate analysis , medicine , history of depression , prospective cohort study , anxiety , physics , transistor , quantum mechanics , voltage , economics , macroeconomics
Objective: That subjects with subthreshold depression have an increased probability of developing major depression has been confirmed by many studies. However, the factors which may predict the onset of major depression have yet to be fully examined. Method: We examined the control group of a randomized trial in primary care patients with subthreshold depression ( N = 109), of whom 20 had developed major depression 1 year later. Using the vulnerability‐stress theory, we examined which factors predicted the onset of major depression. Results: In both univariate and multivariate analyses, family history and chronic illnesses predicted the onset of major depression. Conclusion: It is possible to predict to a certain degree whether a subject with subthreshold depression will develop major depression within a year.