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Is depression related to subsequent diabetes mellitus?
Author(s) -
Akker M.,
Schuurman A.,
Metsemakers J.,
Buntinx F.
Publication year - 2004
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.2004.00333.x
Subject(s) - depression (economics) , diabetes mellitus , medicine , hazard ratio , cohort , retrospective cohort study , population , cohort study , endocrinology , confidence interval , environmental health , economics , macroeconomics
Objective: To compare the risk of developing diabetes mellitus (DM) in the general population between subjects who had a depression and subjects who never had a depression. Method: Retrospective cohort design. People with depression were diagnosed with a depression between 1975 and 1990; controls never had a depression. Both groups were followed for a diagnosis of type II diabetes until 2000. Data on 1334 depressed and 66 670 non‐depressed subjects were available from a large general practice‐based database. Results: No overall relation was found, but among males below age 50 there was a 78% increase in the rate of development of DM compared with non‐depressed patients (hazard ratio 1.78, 95% CI: 1.21–2.62). Conclusion: Depression in males between the age of 20 and 50 years is related to an increased risk of developing DM.