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Neurological abnormalities in patients with schizophrenia or schizophreniform disorder at first admission to hospital: correlations with computerized tomography and regional cerebral blood flow findings
Author(s) -
Rubin P.,
Vorstrup S.,
Hemmingsen R.,
Andersen H. S.,
Bendsen B. B.,
Strømsø N.,
Larsen J. K.,
Bolwig T. G.
Publication year - 1994
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1994.tb01611.x
Subject(s) - cerebral blood flow , schizophrenia (object oriented programming) , schizophreniform disorder , medicine , neurological examination , psychosis , computed tomography , psychology , cardiology , psychiatry , radiology , schizoaffective disorder
Forty‐five patients with schizophrenia or schizophreniform disorder admitted to hospital for the first time had a neurological examination, including integrative sensory and complex motor acts, by a trained neurologist. The patients were studied by CT (computerized tomography) and rCBF (regional cerebral blood flow) as well. A control group of 24 healthy volunteers was included. The patients had significantly more neurological abnormalities (NA) than the healthy volunteers. Medication did not explain the discrepancy. The NA were associated with sulcal enlargement and smaller brains as visualized by CT but not with ventricular enlargement. There was no association between the regional flow values and NA.