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Search for evidence of herpes simplex virus, type 1, or varicella‐zoster virus infection in postmortem brain tissue from schizophrenic patients
Author(s) -
Alexander R. C.,
Cabirac G.,
Lowenkopf T.,
Casanova M.,
Kleinman J.,
Wyatt R. J.,
Kirch D. G.
Publication year - 1992
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1992.tb03290.x
Subject(s) - herpes simplex virus , virology , polymerase chain reaction , virus , varicella zoster virus , herpesviridae , alphaherpesvirinae , medicine , hsl and hsv , biology , viral disease , gene , biochemistry
The highly sensitive polymerase chain reaction (PCR) was used to search for herpes simplex virus type 1 (HSV‐I) or varicella‐zoster virus (VZV) in the DNA extracted from postmortem temporal cortex samples of 8 schizophrenic subjects, 8 nonschizophrenic suicide victims and 8 normal controls. HSV‐I or VZV‐specific DNA amplification was not detected in any of the samples studied.