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Effects of antipsychotic drugs on memory functions of schizophrenic patients
Author(s) -
Eitan N.,
Levin Y.,
BenArtzi E.,
Levy A.,
Neumann M.
Publication year - 1992
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1992.tb01446.x
Subject(s) - haloperidol , chlorpromazine , anticholinergic , thioridazine , antipsychotic , trifluoperazine , typical antipsychotic , risperidone , psychology , schizophrenia (object oriented programming) , memory consolidation , atypical antipsychotic , medicine , psychiatry , pharmacology , neuroscience , calmodulin , dopamine , calcium , hippocampus
In this research we investigated the effects of 4 antipsychotic drugs with different anticholinergic components on different memory functions of schizophrenic patients. Drugs were administrated in cumulative doses and memory was tested 90 min after each drug was administered. The results show that chlorpromazine and thioridazine impaired short‐term verbal memory after 6 h of sequential administration. Trifluoperazine and haloperidol improved short‐term verbal memory from the third to the fifth administration. Immediate memory, long‐term memory and visual short‐term memory were not impaired by any drug.