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Haloperidol and lithium carbonate treatment did not influence serum immunoglobulin levels in schizophrenic and affective patients
Author(s) -
Spivak B.,
Radwan M.,
Bartur P.,
Brandon J.,
Tyano S.,
Weizman A.
Publication year - 1991
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1991.tb03134.x
Subject(s) - haloperidol , lithium (medication) , bipolar disorder , lithium carbonate , psychosis , schizophrenia (object oriented programming) , antibody , medicine , psychology , immunoglobulin m , immunoglobulin g , psychiatry , immunology , dopamine , chemistry , ion , organic chemistry , ionic bonding
Serum immunoglobulin levels were studied in 153 psychiatric patients (87 schizophrenic, 48 bipolar and 18 unipolar patients), and 35 healthy controls. Psychotropic treatments (haloperidol in the schizophrenic patients and lithium in the bipolar affective patients) did not alter serum immunoglobulin levels. Decreased mean IgM serum level was detected in the major affective patients (unipolar and bipolar) compared with normal controls. Nonspecific environmental, infectious, autoimmune and emotional factors that can play a role in the alterations obtained in psychiatric patients are discussed.