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Plasma 3‐methoxy‐4‐hydroxyphenylglycol in manic patients: relationships with clinical variables
Author(s) -
Azorin J. M.,
Pupeschi G.,
Valli M.,
Joanny P.,
Raucoules D.,
Lancon C.,
Tissot R.
Publication year - 1990
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1990.tb06442.x
Subject(s) - grandiosity , psychology , psychosis , schizophrenia (object oriented programming) , clinical psychology , mania , anxiety , depression (economics) , medicine , rating scale , bipolar disorder , psychiatry , cognition , developmental psychology , social psychology , narcissism , economics , macroeconomics
Plasma levels of 3‐methoxy‐4‐hydroxyphenylglycol (MHPG) were found to be significantly higher in manic patients than in age‐ and sex‐matched normal controls ( n = 22). In 18 manic patients plasma MHPG correlated with manic symptoms but not with anxiety, depression, motor behaviour, acute psychosis, schizophrenia and severity of illness. A positive correlation between MHPG and grandiosity items on rating scales suggests a link with cognitive contents and therefore a relationship with central factors.