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Effects of remoxipride on psychomotor performance, alone and in combination with ethanol and diazepam *
Author(s) -
Mattila M. J.,
Manila M. E.
Publication year - 1990
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1990.tb05288.x
Subject(s) - diazepam , psychomotor learning , crossover study , psychology , cognition , effects of sleep deprivation on cognitive performance , sensory system , medicine , anesthesia , neuroscience , alternative medicine , pathology , placebo
The effects of remoxipride, alone and in combination with ethanol and diazepam, on sensory, cognitive, and neuromotor performance were studied in 12 healthy volunteers (7 men, 5 women). The study was of double‐blind, randomized, crossover design with each subject receiving six different single‐dose experimental treatments at six sessions. Tests of sensory, cognitive, and neuromotor functions were carried out, together with subjective assessments. Remoxipride alone seemed to have no effect on the sensory functions measured, but it affected cognitive and neuromotor functions to a limited extent. In general the effects of ethanol and diazepam alone were more pronounced than those of remoxipride. When remoxipride was combined with either ethanol or diazepam, there was a tendency for the effect to