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Platelet 5‐HT uptake in post‐stroke depression
Author(s) -
Barry S.,
Phillips O. M.,
Williams D. C.,
Dinan T. G.
Publication year - 1990
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1990.tb01363.x
Subject(s) - platelet , depression (economics) , serotonin , stroke (engine) , medicine , significant difference , cardiology , receptor , mechanical engineering , engineering , economics , macroeconomics
Serotonin (5‐HT) uptake into platelets is reduced in functionally depressed patients. Depression following stroke (cerebrovascular accident; CVA) is common and severe. Sixteen patients who had suffered a CVA within 6 to 12 months and who were medication‐free had blood taken for measurement of platelet 5‐HT uptake. Seven of these patients were depressed. These were compared with age‐ and sex‐matched hospital controls. No difference in platelet 5‐HT uptake was found across these groups.