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Urinary phenylacetic acid in panic disorder with and without depression
Author(s) -
Sabelli H. C.,
Javaid J. I.,
Fawcett J.,
Kravitz H. M.,
Wynn P.
Publication year - 1990
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1990.tb01347.x
Subject(s) - phenylacetic acid , panic disorder , panic , depression (economics) , excretion , urinary system , medicine , urine , psychiatry , psychology , anxiety , chemistry , biochemistry , economics , macroeconomics
Phenylacetic acid (PAA) excretion was measured in 39 patients who met criteria for panic disorder; 9 of these also had major depression, and 30 did not. Patients with panic and depression excreted 66 ± 23 mg/day of PAA, an amount significantly lower than in normal controls; patients with panic disorder but without depression excreted 104 ± 23 mg/day of PAA (not significantly lower than controls). The results support previous studies indicating that PAA excretion is a marker for depressive disorder.