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Magnetic resonance imaging in Alzheimer's disease, multi‐infarct dementia, alcoholic dementia and Korsakoff's psychosis
Author(s) -
Besson J. A. O.,
Crawford J. R.,
Parker D. M.,
Smith F. W.
Publication year - 1989
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1989.tb03005.x
Subject(s) - dementia , psychosis , psychology , magnetic resonance imaging , psychiatry , alzheimer's disease , disease , medicine , radiology
ABSTRACT— Regional spin lattice relaxation times (T 1 ) measured during nuclear magnetic resonance imagine of the brain were compared in patients with Alzheimer's disease, multi‐infarct dementia, alcoholic dementia, Korsakoff's psychosis and control subjects. Regional differences were found between all patient groups compared with controls and within patient groups, with the exception of the comparison between Korsakoff's psychosis and alcoholic dementia. Correlations between regional T 1 change and cognitive lest scores were also found, with particular emphasis between visuospatial deficits and parietal T 1 . The possible role of T 1 measures in the pathophysiology of these disorders is discussed.